BTBD7 antibody (AA 41-130)

Catalog No. ABIN2170703

Product Details anti-BTBD7 Antibody

Target: BTBD7 (BTB (POZ) Domain Containing 7 (BTBD7))

Binding Specificity: AA 41-130

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTBD7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BTBD7

Target: BTBD7 (BTB (POZ) Domain Containing 7 (BTBD7))

Alternative Name: BTBD7 (BTBD7 Products)

Synonyms: wu:fd08g07 antibody, si:dkeyp-55f12.1 antibody, FUP1 antibody, 5730507E09Rik antibody, 8030448M07 antibody, E130118E17Rik antibody, mKIAA1525 antibody, BTB (POZ) domain containing 7 antibody, BTB domain containing 7 antibody, btbd7 antibody, BTBD7 antibody, Btbd7 antibody

Background:

Synonyms: FUP1, BTB/POZ domain-containing protein 7, BTBD7, KIAA1525

Background: Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity).

Gene ID: 55727

UniProt: Q9P203