BTG1 antibody (PE)

Catalog No. ABIN2170715

The Rabbit Polyclonal anti-BTG1 antibody is suitable to detect BTG1 in samples from Human. It has been validated for IF.

Quick Overview for BTG1 antibody (PE) (ABIN2170715)

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG1 antibody is conjugated to PE

Application: Immunofluorescence (IF)

Product Details anti-BTG1 Antibody (PE)

Purpose: BTG1 Polyclonal Antibody, PE Conjugated

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTG1

Isotype: IgG

Application Details

Application Notes: IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for BTG1

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Alternative Name: Btg1

Background:

Synonyms: B cell translocation gene 1 protein, B cell translocation gene 1, anti prolerative, BTG1 protein, BTG1_HUMAN, BTG2_HUMAN, Protein BTG2, BTG family member 2, NGF-inducible anti-prolerative protein PC3, pheochromacytoma cell-3, nerve growth factor-inducible anti-prolerative, B-cell translocation gene 2, BTG2, TIS21, PC3, TIS21

Background: BTG1 belongs to the BTG family of proteins.FUNCTION: Anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B cell chronic lymphocytic leukemia, translocation t(8,12)(q24,q22) with MYC. BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF), suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398).

Gene ID: 694

UniProt: P62324, P78543

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development