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Claudin 23 antibody (AA 25-81) (AbBy Fluor® 647)

The Rabbit Polyclonal anti-Claudin 23 antibody has been validated for IF (cc) and IF (p). It is suitable to detect Claudin 23 in samples from Human.
Catalog No. ABIN2173211

Quick Overview for Claudin 23 antibody (AA 25-81) (AbBy Fluor® 647) (ABIN2173211)

Target

See all Claudin 23 (CLDN23) Antibodies
Claudin 23 (CLDN23)

Reactivity

  • 34
  • 13
  • 3
  • 1
  • 1
  • 1
Human

Host

  • 34
Rabbit

Clonality

  • 34
Polyclonal

Conjugate

  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Claudin 23 antibody is conjugated to AbBy Fluor® 647

Application

  • 14
  • 12
  • 12
  • 12
  • 11
  • 7
  • 3
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 8
    • 4
    • 2
    • 1
    • 1
    AA 25-81

    Cross-Reactivity

    Human

    Predicted Reactivity

    Mouse,Rat,Dog,Cow,Pig,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Claudin 23

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Claudin 23 (CLDN23)

    Alternative Name

    Claudin 23

    Background

    Synonyms: 2310014B08Rik, Claudin23, CLDN 23, CLDN23, CLDNL.

    Background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80 % sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.

    Pathways

    Cell-Cell Junction Organization, Hepatitis C
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