EPB41L5 antibody (AA 51-150) (Cy7)

Catalog No. ABIN2173868

The Rabbit Polyclonal anti-EPB41L5 antibody is suitable to detect EPB41L5 in samples from Human. It has been validated for IF (cc) and IF (p).

Quick Overview for EPB41L5 antibody (AA 51-150) (Cy7) (ABIN2173868)

Target: EPB41L5 (Erythrocyte Membrane Protein Band 4.1 Like 5 (EPB41L5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB41L5 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-EPB41L5 Antibody (Cy7)

Binding Specificity: AA 51-150

Purpose: EPB41L5 Polyclonal Antibody, Cy7 Conjugated

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPB41L5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPB41L5

Target: EPB41L5 (Erythrocyte Membrane Protein Band 4.1 Like 5 (EPB41L5))

Alternative Name: Epb41l5

Background:

Synonyms: Band 4.1-like protein 5, BE37, E41L5_HUMAN, Epb41l5, erythrocyte membrane protein band 4.1 like 5, KIAA1548.

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. EPB41L5 (erythrocyte membrane protein band 4.1 like 5), also known as BE37 or YMO1, is a 733 amino acid cytoplasmic protein that contains one FERM domain, which it uses to bind CRB1 (crumbs homolog 1). EPB41L5 is a homolog of zebrafish 'mosaic eyes' (moe), and is widely expressed but found at highest levels in ovary, kidney and brain, and is known to colocalize with _-catenin. EPB41L5 may participate in tight junction positioning during the establishment of epithelial cell polarity, and exists as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 2q14.2.