EPB41L5 antibody (AA 51-150) (HRP)

Catalog No. ABIN2173870

This Rabbit Polyclonal antibody specifically detects EPB41L5 in IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for EPB41L5 antibody (AA 51-150) (HRP) (ABIN2173870)

Target: EPB41L5 (Erythrocyte Membrane Protein Band 4.1 Like 5 (EPB41L5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB41L5 antibody is conjugated to HRP

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EPB41L5 Antibody (HRP)

Binding Specificity: AA 51-150

Purpose: EPB41L5 Polyclonal Antibody, HRP Conjugated

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPB41L5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPB41L5

Target: EPB41L5 (Erythrocyte Membrane Protein Band 4.1 Like 5 (EPB41L5))

Alternative Name: EPB41L5

Background:

Synonyms: Band 4.1-like protein 5, BE37, E41L5_HUMAN, Epb41l5, erythrocyte membrane protein band 4.1 like 5, KIAA1548.

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. EPB41L5 (erythrocyte membrane protein band 4.1 like 5), also known as BE37 or YMO1, is a 733 amino acid cytoplasmic protein that contains one FERM domain, which it uses to bind CRB1 (crumbs homolog 1). EPB41L5 is a homolog of zebrafish 'mosaic eyes' (moe), and is widely expressed but found at highest levels in ovary, kidney and brain, and is known to colocalize with _-catenin. EPB41L5 may participate in tight junction positioning during the establishment of epithelial cell polarity, and exists as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 2q14.2.