FEM1B antibody (PE)

Catalog No. ABIN2174122

This Rabbit Polyclonal antibody specifically detects FEM1B in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FEM1B antibody (PE) (ABIN2174122)

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-FEM1B Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FEM 1B

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C for 12 months.

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: Fem 1b

Background: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.Tissue specificity: Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.
Synonyms: F1A-alpha, F1AA, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, Fem1 homolog b, FEM1 like death receptor binding protein, FEM1-beta, FEM1B, FEM1B_HUMAN, Protein fem-1 homolog B.

Gene ID: 10116