FEM1B antibody (AA 531-627)

Catalog No. ABIN873113

Product Details anti-FEM1B Antibody

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Binding Specificity: AA 531-627

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FEM 1B

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: FEM 1B (FEM1B Products)

Synonyms: F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody

Background:

Synonyms: F1AA, F1A-ALPHA, FEM1-beta, Protein fem-1 homolog B, FEM1b, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, KIAA0396

Background: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Gene ID: 10116

UniProt: Q9UK73