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Hepcidin 25 antibody (AA 60-84)

HEPC25 Reactivity: Human IF (p), WB, IF (cc), IHC (p), ELISA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2175579
  • Target See all Hepcidin 25 (HEPC25) Antibodies
    Hepcidin 25 (HEPC25)
    Binding Specificity
    • 29
    • 1
    • 1
    AA 60-84
    Reactivity
    • 16
    • 15
    • 15
    Human
    Host
    • 31
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Hepcidin 25 antibody is un-conjugated
    Application
    • 25
    • 16
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Hepcidin 25
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Hepcidin 25 (HEPC25)
    Alternative Name
    Hepcidin 25 (HEPC25 Products)
    Synonyms
    HEPC antibody, HFE2B antibody, LEAP1 antibody, PLTR antibody, hepcidin antimicrobial peptide antibody, HAMP antibody
    Background

    Synonyms: Hamp, HEPC, HEPC_HUMAN, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.

    Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

    Gene ID
    57817
    UniProt
    P81172
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