HLTF antibody (PE)

Catalog No. ABIN2175888

This anti-HLTF antibody is a Rabbit Polyclonal antibody detecting HLTF in FACS. Suitable for Human, Mouse and Rat.

Quick Overview for HLTF antibody (PE) (ABIN2175888)

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLTF antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-HLTF Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HLTF.

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C for 12 months.

Target Details for HLTF

Target: HLTF (Helicase-Like Transcription Factor (HLTF))

Alternative Name: Hltf

Background: Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Synonyms: DNA-binding protein/plasminogen activator inhibitor 1 regulator, Helicase like transcription factor, Helicase-like transcription factor, HIP116, HIP116A, HLTF 1, HLTF, HLTF_HUMAN, HLTF1, p113, RING finger protein 80, RNF80, SMARC A3, SMARCA 3, SMARCA3, SNF2-like 3, SNF2L3, Sucrose nonfermenting protein 2 like 3, Sucrose nonfermenting protein 2-like 3, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, ZBU 1, ZBU1.

Gene ID: 6596