HNRNPC antibody (PE)

Catalog No. ABIN2175952

This Rabbit Polyclonal antibody specifically detects HNRNPC in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for HNRNPC antibody (PE) (ABIN2175952)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is conjugated to PE

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HNRNPC Antibody (PE)

Purpose: hnRNP C1/C2 Polyclonal Antibody, PE Conjugated

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HNRPC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: Hnrpc

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein C, Heterogeneous nuclear ribonucleoproteins C1/C2, HNRNP, hnRNP C1 / hnRNP C2, hnRNP C1/C2, hnRNPC, HNRPC, HNRPC_HUMAN, Nuclear ribonucleoprotein particle C1 protein, Nuclear ribonucleoprotein particle C2 protein, SNRPC.

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Gene ID: 3183