CD14 antibody
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- Target See all CD14 Antibodies
- CD14
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Reactivity
- Human, Cynomolgus, Pig, Cow, Sheep, Dog, Rabbit, Goat, Cat, Mink, Llama
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD14 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)
- Specificity
- Recognizes the human CD14 cell surface antigen. CD14 is a 55 KDa glycoprotein that contains multiple leucine-rich repeats. It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage but a soluble form of CD14 also exists. CD14 is strongly expressed on the surface of monocytes and macrophages but has also been shown to be expressed on the surface of non-myeloid cells. CD14 functions as a pattern recognition receptor, in innate immunity for a variety of ligands, in particular for the LPS (endotoxin) of Gram-negative bacteria. Has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner.
- Purification
- Protein G purified
- Endotoxin Level
- Low Endotoxin
- Immunogen
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Type of Immunogen: Native protein - Clone
- TÜK4
- Isotype
- IgG2a
- Top Product
- Discover our top product CD14 Primary Antibody
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- Application Notes
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Approved: ELISA, Flo (1:100 - 1:200), Func, WB
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS.
- Handling Advice
- Store undiluted.
- Storage
- -20 °C
- Storage Comment
- -20°C. Store undiluted.
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- Target
- CD14
- Alternative Name
- CD14 (CD14 Products)
- Background
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Name/Gene ID: CD14
Synonyms: CD14, CD14 Molecule, CD14 antigen - Gene ID
- 929
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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