ITGA3 antibody (AA 976-1025) (HRP)

Catalog No. ABIN2177037

This anti-ITGA3 antibody is a Rabbit Polyclonal antibody detecting ITGA3 in WB, ELISA and IHC (p). Suitable for Mouse and Pig.

Quick Overview for ITGA3 antibody (AA 976-1025) (HRP) (ABIN2177037)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivity: Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGA3 Antibody (HRP)

Binding Specificity: AA 976-1025

Cross-Reactivity: Mouse, Pig

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin alpha 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: Integrin alpha 3

Background:

Synonyms: VL3A, CD49C, GAPB3, ILNEB, MSK18, VCA-2, VLA3a, GAP-B3, Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, VLA-3 subunit alpha, ITGA3

Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Gene ID: 3675

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex