ITGA3 antibody (AA 168-276)

Catalog No. ABIN7156434

Product Details anti-ITGA3 Antibody

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Binding Specificity: AA 168-276

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-3 protein (168-276AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: ITGA3 (ITGA3 Products)

Synonyms: CD49C antibody, GAP-B3 antibody, GAPB3 antibody, ILNEB antibody, MSK18 antibody, VCA-2 antibody, VL3A antibody, VLA3a antibody, ITGA3 antibody, AA407068 antibody, integrin subunit alpha 3 antibody, integrin subunit alpha 3 S homeolog antibody, integrin alpha 3 antibody, ITGA3 antibody, itga3.S antibody, Itga3 antibody

Background:

Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Aliases: AA407068 antibody, Antigen identified by monoclonal antibody J143 antibody, CD49 antigen like family member C antibody, CD49 antigen-like family member C antibody, CD49c antibody, CD49c antigen antibody, FLJ34631 antibody, FLJ34704 antibody, FRP 2 antibody, FRP-2 antibody, FRP2 antibody, Galactoprotein B3 antibody, GAP B3 antibody, GAPB3 antibody, Integrin alpha 3 antibody, Integrin alpha-3 light chain antibody, Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody, ITA3_HUMAN antibody, ITGA 3 antibody, Itga3 antibody, MSK18 antibody, VCA 2 antibody, VCA2 antibody, Very late activation protein 3 receptor alpha 3 subunit antibody, VL3A antibody, VLA 3 alpha chain antibody, VLA 3 subunit alpha antibody, VLA-3 subunit alpha antibody, VLA3a antibody

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex