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TAB3 antibody (PE)

TAB3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal PE
Catalog No. ABIN2179514
  • Target See all TAB3 Antibodies
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Reactivity
    • 40
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    • 1
    Rabbit
    Clonality
    • 39
    • 1
    Polyclonal
    Conjugate
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAB3 antibody is conjugated to PE
    Application
    • 24
    • 21
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TAB3
    Isotype
    IgG
    Top Product
    Discover our top product TAB3 Primary Antibody
  • Application Notes
    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Target
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Alternative Name
    Tab3 (TAB3 Products)
    Synonyms
    MAP3K7IP3 antibody, NAP1 antibody, 4921526G09Rik antibody, Map3k7ip3 antibody, mKIAA4135 antibody, map3k7ip3 antibody, nap1 antibody, tab3 antibody, tab3-a antibody, tab3-b antibody, map3k7ip3l antibody, si:ch211-232d19.8 antibody, si:dkey-30h22.6 antibody, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antibody, TAB3 antibody, Tab3 antibody, tab3.S antibody, tab3 antibody
    Background

    Synonyms: MAP3K7IP 3, Mitogen activated protein kinase kinase kinase 7 interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF kappa B activating protein 1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAB3_HUMAN, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3.

    Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

    Gene ID
    257397
    UniProt
    Q8N5C8
    Pathways
    TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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