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SYK antibody (pTyr525, Tyr526)

This Rabbit Polyclonal antibody specifically detects SYK in WB and ELISA. It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN218731

Quick Overview for SYK antibody (pTyr525, Tyr526) (ABIN218731)

Target

See all SYK Antibodies
SYK (Spleen tyrosine Kinase (SYK))

Reactivity

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  • 85
  • 55
  • 10
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  • 1
  • 1
Human, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This SYK antibody is un-conjugated

Application

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Western Blotting (WB), ELISA
  • Binding Specificity

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    pTyr525, Tyr526

    Specificity

    Detects overexpressed levels of Syk protein only when phosphorylated at Tyr525/526 of human Syk or Tyr519/ 520 of mouse Syk. Does not cross-react with other tyrosine-phosphorylated members of the Syk/Zap-70 tyrosine kinase family.

    Purification

    Protein A purified

    Immunogen

    Synthetic phosphopeptide corresponding to residues surrounding Tyr525/526 of human Syk (KLH coupled).

    Type of Immunogen: Synthetic phospho-peptide

    Isotype

    IgG
  • Application Notes

    Approved: ELISA (1:1000), WB (1:1000)

    Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1:1000. ELISA: 1:1000.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

    Preservative

    Without preservative

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    SYK (Spleen tyrosine Kinase (SYK))

    Alternative Name

    SYK

    Background

    Name/Gene ID: SYK
    Subfamily: Syk/ZAP70
    Family: Protein Kinase

    Synonyms: SYK, p72syk, Spleen tyrosine kinase, Syk protein-tyrosine kinase, Tyrosine-protein kinase SYK, p72-Syk

    Gene ID

    6850

    UniProt

    P43405

    Pathways

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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