SYK antibody (pTyr525, Tyr526)
Quick Overview for SYK antibody (pTyr525, Tyr526) (ABIN218731)
Target
See all SYK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr525, Tyr526
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Specificity
- Detects overexpressed levels of Syk protein only when phosphorylated at Tyr525/526 of human Syk or Tyr519/ 520 of mouse Syk. Does not cross-react with other tyrosine-phosphorylated members of the Syk/Zap-70 tyrosine kinase family.
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Purification
- Protein A purified
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Immunogen
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Synthetic phosphopeptide corresponding to residues surrounding Tyr525/526 of human Syk (KLH coupled).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:1000), WB (1:1000)
Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1:1000. ELISA: 1:1000. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Alternative Name
- SYK
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Background
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Name/Gene ID: SYK
Subfamily: Syk/ZAP70
Family: Protein Kinase
Synonyms: SYK, p72syk, Spleen tyrosine kinase, Syk protein-tyrosine kinase, Tyrosine-protein kinase SYK, p72-Syk -
Gene ID
- 6850
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UniProt
- P43405
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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