Surfactant Protein B Cross Reactive with Human Sp-B antibody

Catalog No. ABIN2192158

This Rabbit Polyclonal antibody specifically detects Surfactant Protein B Cross Reactive with Human Sp-B in IA and WB. It exhibits reactivity toward Pig. It has been mentioned in 2+ publications

Quick Overview for Surfactant Protein B Cross Reactive with Human Sp-B antibody (ABIN2192158)

Target: Surfactant Protein B Cross Reactive with Human Sp-B

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Application: Immunoassay (IA), Western Blotting (WB)

Product Details

Sterility: 0.2 μm filtered

Application Details

Application Notes: For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Restrictions: For Research Use only

Handling

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Expiry Date: 12 months

References

Oviedo, Valiño, Plasencia, Serrano, Casals, Pérez-Gil: "Quantitation of pulmonary surfactant protein SP-B in the absence or presence of phospholipids by enzyme-linked immunosorbent assay." in: Analytical biochemistry, Vol. 293, Issue 1, pp. 78-87, (2001) (PubMed).

Pérez-Gil: "Lipid-protein interactions of hydrophobic proteins SP-B and SP-C in lung surfactant assembly and dynamics." in: Pediatric pathology & molecular medicine, Vol. 20, Issue 6, pp. 445-69, (2001) (PubMed).

Target Details

Target: Surfactant Protein B Cross Reactive with Human Sp-B

Background: The polyclonal antibody recognizes the human surfactant protein B (SP-B). There are four surfactant- specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and