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Occludin antibody

OCLN Reactivity: Human WB, IF, IHC (fro) Host: Guinea Pig Polyclonal unconjugated
Catalog No. ABIN2192203
  • Target See all Occludin (OCLN) Antibodies
    Occludin (OCLN)
    Reactivity
    • 102
    • 64
    • 44
    • 34
    • 18
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 87
    • 18
    • 2
    • 1
    Guinea Pig
    Clonality
    • 84
    • 24
    Polyclonal
    Conjugate
    • 44
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Occludin antibody is un-conjugated
    Application
    • 86
    • 34
    • 29
    • 26
    • 26
    • 15
    • 15
    • 14
    • 12
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Sterility
    0.2 μm filtered
    Top Product
    Discover our top product OCLN Primary Antibody
  • Application Notes
    For immunohistology, immunfluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50..
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Van Itallie, Anderson: "Occludin confers adhesiveness when expressed in fibroblasts." in: Journal of cell science, Vol. 110 ( Pt 9), pp. 1113-21, (1997) (PubMed).

  • Target
    Occludin (OCLN)
    Alternative Name
    Occludin (OCLN Products)
    Synonyms
    AI503564 antibody, Ocl antibody, ocln antibody, oclnb antibody, tpmt antibody, OCLN antibody, wu:fd23h10 antibody, wu:fi13c01 antibody, zgc:113992 antibody, zgc:56359 antibody, BLCPMG antibody, occludin antibody, occludin S homeolog antibody, occludin a antibody, Ocln antibody, OCLN antibody, ocln.S antibody, ocln antibody, oclna antibody
    Background
    The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1). The antibody is generated against recombinant human occludin (aa 358-504). The polyclonal anti- human occludin antibody cross reacts with rat, mouse and dog occludin.
    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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