Caspase 7 antibody (N-Term)

Catalog No. ABIN219244

This Rabbit Polyclonal antibody specifically detects Caspase 7 in WB, ELISA, IP and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Caspase 7 antibody (N-Term) (ABIN219244)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Caspase 7 Antibody

Binding Specificity: N-Term

Specificity: Detects endogenous levels of the large fragment of caspase-7 following cleavage at (Asp198). Does not cross-react with full length caspase-7 or with other caspases. Species cross-reactivity: Human, mouse and rat.

Purification: Protein A purified

Immunogen: Synthetic peptide corresponding to N-terminal residues adjacent to (Asp198) in human caspase-7 (KLH coupled).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, ICC, IP (1:100), WB (1:1000)

Usage: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunocytochemistry. Western Blot: 1:1000. Detects a band at ~20kD. Immunoprecipitation: 1:100. Immunocytochemistry (ABC): 1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: CASP7 / Caspase 7

Background: Name/Gene ID: CASP7
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP7, Apoptotic protease Mch-3, Caspase 7, Caspase-7, ICE-LAP3, LICE2, MCH3, ICE-like apoptotic protease 3, CASP-7, CMH-1

Gene ID: 840

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity