CBP antibody

Catalog No. ABIN219299

The Mouse Monoclonal anti-CBP antibody is suitable to detect CBP in samples from Human, Mouse, Rat, Monkey and Mink. It has been validated for WB, IHC, IF and IHC (p).

Quick Overview for CBP antibody (ABIN219299)

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reactivity: Human, Mouse, Rat, Monkey, Mink

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CBP Antibody

Specificity: Recognizes human p300 and CBP. p300 and CBP differ by three noncontiguous residues within the 21aa epitope region. A difference that does not detectably affect the reactivity of LS-C12614. Species cross-reactivity: monkey, mink, mouse and rat.

Purification: Protein A purified

Immunogen: E1A affinity purified p300 protein.

Isotype: IgG2b

Application Details

Application Notes: Approved: IF, IHC, IHC-P, WB

Usage: Suitable for use in Immunofluorescence and Immunohistochemistry. Not suitable for use in Western Blot. Immunohistochemistry (Formalin/paraffin): 1:50-1:100 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for CBP

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Alternative Name: CREBBP / CBP

Background: Name/Gene ID: CREBBP

Synonyms: CREBBP, CREB binding protein, CREB-binding protein, KAT3A, RSTS, Rubinstein-Taybi syndrome, RTS, CBP

Gene ID: 1387

UniProt: Q92793

Pathways: TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha