SPTAN1 antibody (N-Term)
Quick Overview for SPTAN1 antibody (N-Term) (ABIN222390)
Target
See all SPTAN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- Detects endogenous levels of the large fragment of alpha-fodrin resulting from cleavage by caspase (s) at Asp1185. The antibody does not recognize full length alpha-fodrin.
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Purification
- Protein A purified
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Immunogen
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Synthetic peptide (KLH coupled) corresponding to N-terminal residues adjacent to Asp1185 in human alpha-fodrin.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA, WB (1:1000)
Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1:1000. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
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Preservative
- Without preservative
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- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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Alternative Name
- SPTAN1 / Alpha Fodrin
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Background
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Name/Gene ID: SPTAN1
Synonyms: SPTAN1, Alpha-II spectrin, Alpha Fodrin, Fodrin alpha chain, EIEE5, NEAS, Alpha-fodrin, Spectrin alpha chain, brain, SPTA2 -
Gene ID
- 6709
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UniProt
- Q13813
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
Target
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