LILRB3 antibody (FITC)

Catalog No. ABIN225572

Product Details anti-LILRB3 Antibody (FITC)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LILRB3 antibody is conjugated to FITC

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.

Purification: Protein G purified

Immunogen: Monocyte derived dendritic cells.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1 - 1:10), IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: LILRB3 (LILRB3 Products)

Background: Name/Gene ID: LILRB3
Family: Immunoglobulin

Synonyms: LILRB3, CD85A, CD85a antigen, ILT5, LIR-3, LIR3, Monocyte inhibitory receptor, HL9, ILT-5

Gene ID: 11025