LILRB3 antibody (AA 400-500)

Catalog No. ABIN7268239

This Rabbit Polyclonal antibody specifically detects LILRB3 in WB. It exhibits reactivity toward Human.

Quick Overview for LILRB3 antibody (AA 400-500) (ABIN7268239)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LILRB3 Antibody

Binding Specificity: AA 400-500

Purpose: LILRB3 Rabbit pAb

Sequence: RSSNPHLLSF PSEPLELMVS GHSGGSSLPP TGPPSTPGGP EDQPLNPPGS GPQNGLGRYL EVLIGVSVAF VLLLFLLLFL LLLRQRHSKH RTSDQRKTDF Q

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human LILRB3 (NP_001307889.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: LILRB3

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB3,CD85A,HL9,ILT-5,ILT5,LILRA6,LIR-3,LIR3,PIR-B,PIRB,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,LILRB3

Molecular Weight: 69kDa/71kDa

Gene ID: 11025

UniProt: O75022