Glycogen Synthase 1 antibody (pSer641)

Catalog No. ABIN228217

This Rabbit Polyclonal antibody specifically detects Glycogen Synthase 1 in WB, IHC, IP and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Glycogen Synthase 1 antibody (pSer641) (ABIN228217)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: pSer641

Specificity: Detects both muscle and liver isoforms of glycogen synthase only when phosphorylated at serine 640 or 641 of muscle and liver isoforms, respectively.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser641 of human liver glycogen synthase.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, IP (1:100), WB (1:1000)

Usage: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry. Western Blot: 1:1000. Immunoprecipitation: 1:100. Immunohistochemistry (Paraffin): 1:25.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1 / Glycogen Synthase

Background: Name/Gene ID: GYS1

Synonyms: GYS1, Glycogen synthase 1 (muscle), GSY, GYS

Gene ID: 2997

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process