PKC zeta antibody (pThr410, Thr403)
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- Target See all PKC zeta (PRKCZ) Antibodies
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
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Binding Specificity
- pThr410, Thr403
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PKC zeta antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Detects endogenous human PKC zeta only when phosphorylated at Thr410, or endogenous human PKC lambda only when phosphorylated at Thr403. Does not cross-react with endogenous levels of other PKC isoforms. Species cross-reactivity: monkey, rat and mouse.
- Purification
- Protein A purified
- Immunogen
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Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Thr410 of human PKC zeta.
Type of Immunogen: Synthetic phospho-peptide - Isotype
- IgG
- Top Product
- Discover our top product PRKCZ Primary Antibody
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- Application Notes
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Approved: ELISA, IHC, IHC-P, WB (1:1000)
Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Immunohistochemistry (paraffin): 1:50. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
- Alternative Name
- PRKCZ / PKC-Zeta (PRKCZ Products)
- Synonyms
- TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
- Background
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Name/Gene ID: PRKCZ
Subfamily: PKC
Family: Protein Kinase
Synonyms: PRKCZ, PKC-ZETA, PKC2, Pkcz, PKCzeta, Protein kinase c zeta, Protein kinase C zeta type, NPKC-zeta, PKC Zeta, Protein kinase C, zeta, Protein kinase Czeta - Gene ID
- 5590
- UniProt
- Q05513
- Pathways
- NF-kappaB Signaling, RTK Signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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