MTOR antibody (pSer2448)

Catalog No. ABIN2308337

The Rabbit Monoclonal anti-MTOR antibody has been validated for WB, IF and IP. It is suitable to detect MTOR in samples from Human.

Quick Overview for MTOR antibody (pSer2448) (ABIN2308337)

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTOR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 11C1050

Product Details anti-MTOR Antibody

Binding Specificity: pSer2448

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Calculated cross reactivity: Hu Mo Rt

Characteristics: mTOR, phosphorylated (Ser2448) (Mammalian Target of Rapamycin, Mechanistic Target of Rapamycin, Serine/threonine Protein Kinase mTOR, FK506-binding Protein 12-rapamycin Complex-associated Protein 1, FKBP12-rapamycin Complex-associated Protein, FRAP, FRAP1, FRAP2, FLJ44809, RAFT1, Rapamycin Target Protein 1, RAPT1)

Purification: Purified

Immunogen: Synthetic peptide corresponding to residues surrounding Ser2448 of human mTOR.

Isotype: IgG

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, less than 0.02 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Alternative Name: mTOR

UniProt: P42345

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect