IL-6 Receptor antibody (Biotin)

Catalog No. ABIN233222

The Mouse Monoclonal anti-IL-6 Receptor antibody has been validated for FACS and Func. It is suitable to detect IL-6 Receptor in samples from Human.

Quick Overview for IL-6 Receptor antibody (Biotin) (ABIN233222)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Functional Studies (Func)

Product Details anti-IL-6 Receptor Antibody (Biotin)

Specificity: Recognizes the gp80 chain of human IL-6 Receptor (IL-6R).

Purification: Purified

Immunogen: Interleukin 6 Receptor, gp80.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func

Usage: Suitable for use in Flow Cytometry and Functional Studies. Inhibition of proliferation by 50 % . The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM Tris, 100 mM sodium chloride, 0.02 % sodium azide,  pH 7.4, 1 % BSA, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R / IL6 Receptor

Background: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints