CHRM4 antibody (AA 469-478)
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- Target See all CHRM4 Antibodies
- CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))
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Binding Specificity
- AA 469-478
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHRM4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Shown to be specific for the COOH terminal of the M4 receptor. Cross-reactivity: M4 Muscarinic Receptor (aa469-478): 100 % , M4 Muscarinic Receptor: ~70 %. No reactivity is observed with M1-M3, M5 (full receptors), M1 (aa451-460), M2 (aa457-466), M3 Muscarinic Receptor (aa580-589), M5 (aa519-531).
- Purification
- Ammonium sulfate precipitation
- Immunogen
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Peptide analogue of the carboxyl terminal of the M4 receptor covalently attached onto a carrier protein.
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product CHRM4 Primary Antibody
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- Application Notes
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Approved: ELISA, IHC (50 μg/mL), WB
Usage: Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications have been tested. Immunohistochemistry: 50 μg/mL stains PLP fixed cultured cells known to express the Muscarinic Receptor M4. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.2, 10 mg/mL BSA, 40 % glycerol.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))
- Alternative Name
- CHRM4 / M4 (CHRM4 Products)
- Synonyms
- M3R antibody, M4 antibody, HM4 antibody, M4R antibody, Chrm-4 antibody, cholinergic receptor muscarinic 4 antibody, cholinergic receptor, muscarinic 4 antibody, CHRM4 antibody, chrm4 antibody, Chrm4 antibody
- Background
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Name/Gene ID: CHRM4
Subfamily: Acetylcholine
Family: GPCR
Synonyms: CHRM4, M4 muscarinic receptor, M4R, Muscarinic m4 receptor, HM4, Muscarinic receptor m4 - Gene ID
- 1132
- UniProt
- P08173
- Pathways
- cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane
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