PDGFRB antibody (pTyr751)
Quick Overview for PDGFRB antibody (pTyr751) (ABIN233637)
Target
See all PDGFRB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr751
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Specificity
- Detects endogenous levels of PDGF receptor beta only when phosphorylated at Tyr751 (190kD). Does not cross-react with other tyrosine-phosphorylated proteins. Species cross-reactivity: Human, mouse, rat.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide corresponding to residues surrounding Tyr751of human PDGF receptor beta (KLH coupled).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: Flo (1:200), WB (1:1000)
Usage: Suitable for use in Western Blot and Flow Cytometry. Western Blot: 1:1000. Flow Cytometry: 1:200. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, BSA, 0.02 % sodium azide, 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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Alternative Name
- PDGFRB / PDGFR Beta
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Background
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Name/Gene ID: PDGFRB
Subfamily: PDGF Receptor
Family: Protein Kinase
Synonyms: PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene -
Gene ID
- 5159
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UniProt
- P09619
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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