Progesterone Receptor antibody

Catalog No. ABIN233669

The Mouse Monoclonal anti-Progesterone Receptor antibody is suitable to detect Progesterone Receptor in samples from Human, Rabbit, Chicken and Cow. It has been validated for IF and IP.

Quick Overview for Progesterone Receptor antibody (ABIN233669)

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rabbit, Chicken, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Progesterone Receptor Antibody

Specificity: Recognizes only a protein of 116kD (triplet) which is identified as the hormone-binding high MW (B) form of human PgR. Reacts with Human, bovine, Rabbit and Chicken. Does not react with monkey.

Purification: Protein A purified

Immunogen: PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice.

Type of Immunogen: Purified protein

Isotype: IgG2b

Application Details

Application Notes: Approved: IF, IP

Usage: Immunofluorescence. Immunoprecipitation (Use Protein A). (Ab at 2 μg/mg protein lysate). Sedimentation in Sucrose Gradient. Cellular Localization: Nuclear. Positive control: T47D cells or breast carcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4, 0.2 % BSA, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR/Progesterone Receptor

Background: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration