CD42b antibody

Catalog No. ABIN234642

Product Details anti-CD42b Antibody

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42b antibody is un-conjugated

Application: Flow Cytometry (FACS)

Cross-Reactivity (Details): The molecular weight of the recognized antigen is 160kDa. Reacts with glycoprotein Ib on megakaryocytes and platelets. Inhibits the ristocetin-dependent binding of Von Willebrand factor to platelets and ristocetin induced platelet agglutination. Inhibits platelet aggregation induced by Type I collagen and platelet activating factor (PAF). Immunoprecipitates the components of glycoprotein Ib complex.

Characteristics: MAb to CD42b gpIb, Monoclonal antibody to Human CD42b gpIb

Purification: Ion Exchange or affinity Chromatography. Ascites

Immunogen: Human washed platelets

Clone: SZ2

Isotype: IgG1

Application Details

Application Notes: Suitable for use in flow cytometry: 2-g / 5 x 106 platelets/test. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL distilled water.

Buffer: Lyophilized from PBS containing 1 mg/mL BSA.

Preservative: Without preservative

Handling Advice: Avoid multiple freeze/thaw cycles. The addition of 0.1 % (w/v) sodium azide is recommended for storage of the Reconstituted form for up to 1 month at 2-8 °C.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized product at 2-8 °C. After reconstitution, aliquot and store at -28 °C.

Target Details for CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Abstract: GP1BA Products