ADAM17 antibody (AA 1-671)

Catalog No. ABIN2370987

Cited in 1 publication. The Mouse Monoclonal anti-ADAM17 antibody (Clone 11C154) (ABIN2370987) specifically detects ADAM17 in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for ADAM17 antibody (AA 1-671) (ABIN2370987)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADAM17 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 11C154

Product Details anti-ADAM17 Antibody

Binding Specificity: AA 1-671

Cross-Reactivity: Human

Cross-Reactivity (Details): Calculated cross reactivity: Hu

Characteristics: TACE (Disintegrin and Metalloproteinase Domain-containing Protein 17, TNF-alpha-converting Enzyme, TNF-alpha Convertase, Snake Venom-like Protease, CD156b Antigen, CSVP, TNF-a Converting Enzyme, ADAM17)

Purification: Purified by affinity chromatography.

Immunogen: Human TACE pure protein (Extracellular domain, aa1-671).

Isotype: IgG

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 100 μL sterile ddH2O.

Buffer: Supplied as a lyophilized powder from PBS, pH 7.5.

Storage: -20 °C

Storage Comment: -20°C

References for anti-ADAM17 antibody (ABIN2370987)

Six, Debaene, Van den Hauwe, De Rycke, Gardiner, Compernolle, Feys: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." in: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: TACE

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus