ESAT6 antibody

Catalog No. ABIN238348

This Rabbit Polyclonal antibody specifically detects ESAT6 in WB. It exhibits reactivity toward Mycobacterium tuberculosis.

Quick Overview for ESAT6 antibody (ABIN238348)

Target: ESAT6

Reactivity: Mycobacterium tuberculosis

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Specificity: The polyclonal antibody reacts with EsaT-6, a 11,8 kDa antigen encoded by gene Rv3875 of Mycobacterium tuberculosis. The antibody recognizes EsaT-6 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis. It reacts also with recombinant antigen produced in Escherichia coli.

Purification: Affinity Chromatography on Protein A

Immunogen: EsaT-6 (Rv3875) of Mycobacterium tuberculosis.

Application Details

Application Notes: Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: ESAT6

Background: The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response.Synonyms: 6 kDa early secretory antigenic target, MT3989, MTV027.10, Rv3875, esaT-6, esxA

Gene ID: 886209

NCBI Accession: NP_338543

UniProt: P0A564