TSHB antibody

Catalog No. ABIN238514

The Mouse Monoclonal anti-TSHB antibody is suitable to detect TSHB in samples from Human. It has been validated for EIA and RIA.

Quick Overview for TSHB antibody (ABIN238514)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSHB antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Clone: TSH-116

Product Details anti-TSHB Antibody

Specificity: The antibody TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-116 reacts with association constant 1.1 x 1011 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).

Characteristics: Synonyms: hTSH, Thyroid-stimulating hormone

Purification: Protein A affinity chromatography.

Immunogen: Human thyrotropin.

Isotype: IgG2a

Application Details

Application Notes: ELISA. RIA. The antibody TSH-116 is suitable in combination with the antibody TSH-51 (ABIN238515)for Immunometric assays in the screening of neonatal hypothyroidism.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Alternative Name: Thyrotropin beta Chain

Background: Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha and beta.Synonyms: TSH, TSH beta, TSHB, Thyroid-stimulating hormone subunit beta, Thyrotropin subunit beta

Gene ID: 7252

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism