TAB3 antibody (Internal Region)

Catalog No. ABIN238581

The Goat Polyclonal anti-TAB3 antibody (ABIN238581) specifically detects TAB3 in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for TAB3 antibody (Internal Region) (ABIN238581)

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TAB3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-TAB3 Antibody

Binding Specificity: Internal Region

Purpose: MAP3K7IP3 (aa 59 to 69)

Sequence: HSPDDNRMNR N

Cross-Reactivity: Human, Mouse

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-HSPDDNRMNRN, from the internal region of the protein sequence according to NP_690000.2.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Thyroid. Recommended concentration: 3.75 μg/mL.

Western Blot: Preliminary experiments gave an approx 100 kDa band in Human Kidney lysates after 0.5 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 78.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TAB3

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Alternative Name: MAP3K7IP3

Background: MAP3K7IP3, mitogen-activated protein kinase kinase kinase 7 interacting protein 3, MGC45404, NAP1, TAB3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAK1 binding prote

Gene ID: 257397, 66724

NCBI Accession: NP_690000

Pathways: TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades