ACVR1 antibody (Internal Region)

Catalog No. ABIN238620

The Goat Polyclonal anti-ACVR1 antibody (ABIN238620) specifically detects ACVR1 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for ACVR1 antibody (Internal Region) (ABIN238620)

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ACVR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Grade: Verified

Product Details anti-ACVR1 Antibody

Binding Specificity: Internal Region

Purpose: ACVR1

Sequence: RKFKRRNQER LNPRD

Specificity: Reported variants represent identical protein: NP_001096.1, NP_001104537.1

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-RKFKRRNQERLNPRD, from the internal region of the protein sequence according to NP_001096.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Testis shows preferential staining of cytoplasm in primary spermatocytes.. Recommended concentration, 4-6 μg/mL.

Western Blot: Approx 60 kDa band observed in Human Umbilical Cord lysates (calculated MW of 57.2 kDa according to NP_001096.1). Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Alternative Name: ACVR1

Background: ACVR1, activin A receptor, type I, ACTRI, ACVRLK2, ALK2, FOP, SKR1, activin A receptor, type II-like kinase 2, activin A type I receptor, hydroxyalkyl-protein kinase

Gene ID: 90, 11477, 79558

NCBI Accession: NP_001096