TGFBR1 antibody

Catalog No. ABIN2426967

This anti-TGFBR1 antibody is a Rabbit Polyclonal antibody detecting TGFBR1 in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for TGFBR1 antibody (ABIN2426967)

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-TGFBR1 Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human TGFBR1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TGFBR1

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Alternative Name: TGF beta Receptor I

Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_001124388

Pathways: Growth Factor Binding