Spastin antibody

Catalog No. ABIN2433051

The Rabbit Polyclonal anti-Spastin antibody (ABIN2433051) specifically detects Spastin in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Spastin antibody (ABIN2433051)

Target: Spastin (SPAST)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Spastin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Spastin Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human SPAST

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Spastin

Target: Spastin (SPAST)

Alternative Name: SPAST

Background: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

NCBI Accession: NP_055761

Pathways: Microtubule Dynamics, M Phase, Regulation of Cell Size