HIP1R antibody (C-Term)

Catalog No. ABIN2443743

The Rabbit Polyclonal anti-HIP1R antibody (ABIN2443743) specifically detects HIP1R in WB and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for HIP1R antibody (C-Term) (ABIN2443743)

Target: HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1R antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-HIP1R Antibody

Binding Specificity: C-Term

Purpose: Huntingtin-Interacting Protein 1-Related (HIP1R) Rabbit Polyclonal Antibody

Specificity: The antibody recognizes the C-terminal portion of HIP1R

Purification: Purified

Immunogen: peptide in C term

Application Details

Application Notes: WB 1:500-1:2500,IF 1:50-1:250

Restrictions: For Research Use only

Handling

Reconstitution: If diluted with deionized water in 100 μL: WB 1:500-1:2500, IF 1:50-1:250. Optimal dilution has to be determined by the user.

Buffer: Immunogen affinity purified in glycerol/PBS pH 7.4

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Antibodies diluted in glycerol can be kept at 4°C for up to 2 months and should be kept at -20°C for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20°C or 2 months 4°C) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.

Expiry Date: 12 months

Target Details for HIP1R

Target: HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))

Alternative Name: Huntingtin-Interacting Protein 1-Related (HIP1R)

Background:

HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R

HIP1R (huntingtin interacting protein 1 related) was first cloned based on its sequence similarity with HIP1 (Huntingtin Interacting Protein 1). HIP1 binds to normal huntingtin but this interaction is lost in Huntington's disease (HD). HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1R colocalizes with and binds to actin and this interaction may link the endocytic machinery to the actin cytoskeletal dynamic processes.

UniProt: O75146