ARHGDIA antibody

Catalog No. ABIN2443837

This Rabbit Polyclonal antibody specifically detects ARHGDIA in WB. It exhibits reactivity toward Human.

Quick Overview for ARHGDIA antibody (ABIN2443837)

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARHGDIA Antibody

Purpose: RhoGDI alpha Rabbit Polyclonal Antibody

Specificity: The antibody recognizes the human RhoGDI alpha protein.

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 100 μL: WB 1:1000 - 1:2000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Preservative: Without preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Expiry Date: 24 months

Target Details for ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: RhoGDI alpha

Background:

Rho GDP-dissociation inhibitor 1, RhoGDI alpha

Rho GDP-dissociation inhibitor 1 (RhoGDI alpha) belongs to the Rho GDI family of proteins. It is found in the cytoplasm where it regulates the GDP/GTP exchange reaction of the Rho, Rac and Cdc42 proteins by inhibiting their dissociation from GDP, and their subsequent binding to GTP. Rho, Rac and Cdc42 are molecular switches involved in the regulation of cytoskeletal structures that affect the regulation of cell morphology, movement, attachment, phagocytosis and cytokinesis.

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway