RAD51 antibody

Catalog No. ABIN2452093

Product Details anti-RAD51 Antibody

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reactivity: Human, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This RAD51 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Cross-Reactivity: Rat (Rattus), Chicken

Purification: Purified

Isotype: IgY

Application Details

Application Notes: 1) Western blotting: 1,000~5,000 fold dilution
2) Immunoprecipitation
3) Detection of foci formation by indirect immunofluorescence method

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 100 mM NaCl, 20 mM phosphate buffer ( pH 7.4), 50 % glycerol

Preservative: Azide free

Storage: -20 °C

Target Details for RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Alternative Name: Rad51 (RAD51 Products)

Background: Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs, Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.

UniProt: Q06609

Pathways: DNA Damage Repair