CD248 antibody (full length)
Quick Overview for CD248 antibody (full length) (ABIN2452152)
Target
See all CD248 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- full length
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Characteristics
- Rabbit polyclonal antibody affinity purified with the immunogen after adsorption of anti-GST antibody with GST-affinity column.
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Purification
- Affinity purified
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Immunogen
- GST-full length Tem1 fusion protein expressed in E. coli
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Isotype
- IgG
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Application Notes
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1) Western blotting: 1/250~1/500
2) Immunoprecipitation -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, 1 mg/mL BSA as carrier, 0.09 % sodium azide, 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- CD248 (CD248 Molecule, Endosialin (CD248))
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Alternative Name
- Tem1
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Background
- Background: Tem1 is a low-molecular-weight GTP-binding protein (GTPase) which is required for the termination of M phase in cell division. The defect of Tem1 was lethal, and the Tem1-defective cells were arrested at telophase with high H1-kinase activity, indicating that Tem1 is required to exit from M phase. The defect of Tem1 was suppressed by a high dose of cdc15, which encodes a protein kinase. Tem1 functions upstream of cdc15 kinase and may be required to activate the cdc15 protein kinase pathway. A cascade consisting of Tem1 and kinases act to terminate mitosis.
Target
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