HOXA5 antibody

Catalog No. ABIN2458391

The Rabbit Polyclonal anti-HOXA5 antibody has been validated for WB and ELISA. It is suitable to detect HOXA5 in samples from Human, Rat, Mouse and Drosophila melanogaster.

Quick Overview for HOXA5 antibody (ABIN2458391)

Target: HOXA5 (Homeobox A5 (HOXA5))

Reactivity: Human, Rat, Mouse, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOXA5 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXA5.

Application Details

Application Notes: HOXA5 antibody can be used for detection of HOXA5 by ELISA at 1:312500. HOXA5 antibody can be used for detection of HOXA5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HOXA5 antibody at -20 °C.

Target Details for HOXA5

Target: HOXA5 (Homeobox A5 (HOXA5))

Alternative Name: HOXA5

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of the gene encoding HOXA5 may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 30 kDa

Gene ID: 3202

NCBI Accession: NP_061975

UniProt: A2D5Y4