RHBDF1 antibody
Quick Overview for RHBDF1 antibody (ABIN2459330)
Target
See all RHBDF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RHBDF1.
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Application Notes
- RHBDF1 antibody can be used for detection of RHBDF1 by ELISA at 1:62500. RHBDF1 antibody can be used for detection of RHBDF1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RHBDF1 antibody at -20 °C.
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- RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))
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Alternative Name
- RHBDF1
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Background
- RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
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Molecular Weight
- 97 kDa
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Gene ID
- 64285
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NCBI Accession
- NP_071895
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UniProt
- Q96CC6
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Pathways
- EGFR Signaling Pathway, Growth Factor Binding
Target
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