ACTR1A antibody

Catalog No. ABIN2460043

Product Details anti-ACTR1A Antibody

Target: ACTR1A (Alpha Centractin (ACTR1A))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACTR1A.

Application Details

Application Notes: ACTR1A antibody can be used for detection of ACTR1A by ELISA at 1:62500. ACTR1A antibody can be used for detection of ACTR1A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ACTR1A antibody at -20 °C.

Target Details for ACTR1A

Target: ACTR1A (Alpha Centractin (ACTR1A))

Alternative Name: ACTR1A (ACTR1A Products)

Synonyms: ARP1 antibody, CTRN1 antibody, Arp1 antibody, alpha-Arp1 antibody, arp1 antibody, centractin antibody, ctrn1 antibody, ACTR1A antibody, ARP1 actin related protein 1 homolog A antibody, ARP1 actin-related protein 1A, centractin alpha antibody, ARP1 actin-related protein 1 homolog A, centractin alpha antibody, ARP1 actin related protein 1 homolog A L homeolog antibody, alpha-centractin antibody, actin-2 antibody, ACTR1A antibody, Actr1a antibody, actr1a.L antibody, actr1a antibody, PTRG_02540 antibody, PAAG_06972 antibody, MCYG_01044 antibody, VDBG_00685 antibody, MGYG_00946 antibody, DICPUDRAFT_88548 antibody, PGTG_04034 antibody, Tsp_06409 antibody

Background: ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 41 kDa

Gene ID: 10121

NCBI Accession: NP_005727

UniProt: P61163

Pathways: M Phase