L3MBTL2 antibody

Catalog No. ABIN2460164

The Rabbit Polyclonal anti-L3MBTL2 antibody is suitable to detect L3MBTL2 in samples from Human and Dog. It has been validated for WB, ELISA and IHC.

Quick Overview for L3MBTL2 antibody (ABIN2460164)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-L3MBTL2 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL2.

Application Details

Application Notes: L3MBTL2 antibody can be used for detection of L3MBTL2 by ELISA at 1:312500. L3MBTL2 antibody can be used for detection of L3MBTL2 by western blot at 0.625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store L3MBTL2 antibody at -20 °C.

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2

Background: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

Molecular Weight: 79 kDa

Gene ID: 83746

NCBI Accession: NP_113676

UniProt: Q969R5