KIN antibody

Catalog No. ABIN2460415

This Rabbit Polyclonal antibody specifically detects KIN in WB and ELISA. It exhibits reactivity toward Human, Rat and Dog.

Quick Overview for KIN antibody (ABIN2460415)

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KIN Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIN.

Application Details

Application Notes: KIN antibody can be used for detection of KIN by ELISA at 1:312500. KIN antibody can be used for detection of KIN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIN antibody at -20 °C.

Target Details for KIN

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Alternative Name: KIN

Background: Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.

Molecular Weight: 45 kDa

Gene ID: 22944

NCBI Accession: NP_036443

UniProt: O60870