SND1 antibody

Catalog No. ABIN2460503

The Rabbit Polyclonal anti-SND1 antibody is suitable to detect SND1 in samples from Human, Mouse, Rat, Dog and Zebrafish (Danio rerio). It has been validated for WB and ELISA.

Quick Overview for SND1 antibody (ABIN2460503)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SND1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SND1.

Application Details

Application Notes: SND1 antibody can be used for detection of SND1 by ELISA at 1:62500. SND1 antibody can be used for detection of SND1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SND1 antibody at -20 °C.

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1

Background: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

Molecular Weight: 100 kDa

Gene ID: 27044

NCBI Accession: NP_055205

UniProt: Q7KZF4