Metabotropic Glutamate Receptor 6 antibody

Catalog No. ABIN2460511

This Rabbit Polyclonal antibody specifically detects Metabotropic Glutamate Receptor 6 in WB and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Dog.

Quick Overview for Metabotropic Glutamate Receptor 6 antibody (ABIN2460511)

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Metabotropic Glutamate Receptor 6 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRM6.

Application Details

Application Notes: GRM6 antibody can be used for detection of GRM6 by ELISA at 1:62500. GRM6 antibody can be used for detection of GRM6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GRM6 antibody at -20 °C.

Target Details for Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Alternative Name: GRM6

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.

Molecular Weight: 95 kDa

Gene ID: 2916

NCBI Accession: NP_000834

UniProt: O15303