PSMC3 antibody
-
- Target See all PSMC3 Antibodies
- PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
-
Reactivity
- Human, Mouse, Dog
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PSMC3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3.
- Top Product
- Discover our top product PSMC3 Primary Antibody
-
-
- Application Notes
- PSMC3 antibody can be used for detection of PSMC3 by ELISA at 1:312500. PSMC3 antibody can be used for detection of PSMC3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMC3 antibody at -20 °C.
-
- Target
- PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
- Alternative Name
- PSMC3 (PSMC3 Products)
- Synonyms
- TBP1 antibody, TBP-1 antibody, wu:fb39a02 antibody, zgc:86713 antibody, psmc3 antibody, MGC89608 antibody, PSMC3 antibody, NV15940 antibody, 23.m06430 antibody, DDBDRAFT_0186002 antibody, DDBDRAFT_0232967 antibody, DDB_0186002 antibody, DDB_0232967 antibody, psmc3-b antibody, tbp10 antibody, psmc3-a antibody, proteasome 26S subunit, ATPase 3 antibody, proteasome (prosome, macropain) 26S subunit, ATPase 3 antibody, 26S protease regulatory subunit 6A antibody, 26S protease regulatory subunit 6a antibody, 26S protease regulatory subunit 6A-B antibody, 26S protease regulatory subunit 6A, putative antibody, proteasome 26S subunit, ATPase 3 S homeolog antibody, nth-like DNA glycosylase 1 S homeolog antibody, PSMC3 antibody, Psmc3 antibody, HCAG_00069 antibody, GL50803_4365 antibody, EDI_316920 antibody, CpipJ_CPIJ006888 antibody, CpipJ_CPIJ006889 antibody, CpipJ_CPIJ010864 antibody, prs6a antibody, psmc3 antibody, LOC100115023 antibody, BBOV_IV004580 antibody, CGB_M2140W antibody, psmC3 antibody, LOC100637883 antibody, psmc3.S antibody, nthl1.S antibody
- Background
- PSMC3 is a subunit of the 26S proteasome. 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9
- Molecular Weight
- 45 kDa
- Gene ID
- 5702
- NCBI Accession
- NP_002795
- UniProt
- Q6IBS1
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
-