LIM Domain Binding 2 Protein antibody

Catalog No. ABIN2460631

Product Details anti-LIM Domain Binding 2 Protein Antibody

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 2 Protein antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LDB2.

Application Details

Application Notes: LDB2 antibody can be used for detection of LDB2 by ELISA at 1:1562500. LDB2 antibody can be used for detection of LDB2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LDB2 antibody at -20 °C.

Target Details for LIM Domain Binding 2 Protein

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Alternative Name: LDB2 (LDB2 Products)

Synonyms: CLIM1 antibody, LDB1 antibody, AI035351 antibody, AW146358 antibody, CLP-36 antibody, Ldb3 antibody, CLIM-1 antibody, LDB2 antibody, ldb2 antibody, clim1 antibody, clim1b antibody, ldb2l antibody, ldb3 antibody, wu:fd16f11 antibody, zgc:92548 antibody, LIM domain binding 2 antibody, LIM domain binding 2a antibody, LIM domain binding 2 S homeolog antibody, LIM domain binding 2b antibody, LDB2 antibody, Ldb2 antibody, ldb2a antibody, ldb2.S antibody, ldb2b antibody

Background: LDB2 belongs to the LDB family. LDB2 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. LIM domains are required for both inhibitory effects on LIM homeodomain transcription factors and synergistic transcriptional activation events. The inhibitory actions of the LIM domain can often be overcome by the LIM co-regulators known as CLIM2, LDB2 and NLI. LIM homeoproteins and CLIMs are involved in a variety of developmental processes.

Molecular Weight: 43 kDa

Gene ID: 9079

NCBI Accession: NP_001281

UniProt: O43679

Pathways: Stem Cell Maintenance